Friday, August 21, 2020

Prostate Cancer Causes And Treatment Health And Social Care Essay Free Essays

string(138) that prostatic tissue cells called â€Å" Basal root cells † are the most probable culprit in explore lab preliminaries done on mice. This paper will investigate a few diverse scholarly journal articles and some well known media articles that are about prostatic dangerous neoplastic sickness. These articles talk about prostate dangerous neoplastic ailment causes, ( approximated and known ) , detecting strategies, and mediation choices. A pair of the articles other than center around the expense of mediation for patients, each piece great as the risks engaged with the varying techniques for intercession. We will compose a custom article test on Prostate Cancer Causes And Treatment Health And Social Care Essay or on the other hand any comparable subject just for you Request Now A few intercession choices for prostate harmful neoplastic infection are as yet being contemplated. This paper will fundamentally dissect and analyze prostatic dangerous neoplastic sickness detecting strategies, (, for example, Prostate-explicit antigen or ( PSA ) preliminaries ) mediation alternatives, and the contrasting achievement or disappointment of every technique, each piece great as focusing on the expanding cost of intercession that patients are compelled to pay. A portion of the articles other than recommend that more assets and more guidance are expected to help bring down the death rate from prostate dangerous neoplastic ailment. This paper will look into what is being done to help bring down the death rate each piece great as what is being done to help increment the pace of early detecting of prostate threatening neoplastic malady. Watchwords: Prostate-explicit antigen Prostate Cancer: Causes and Treatment Options Available in Today ‘s Scientifically Advanced Society Fitting to the Prostate Cancer Foundation, prostate harmful neoplastic malady happens when cells inside the prostate develop wildly, making little tumors. The term â€Å" threatening neoplastic illness † alludes to a status wherein the statute of cell developing is lost and cells develop wildly. Prostate threatening neoplastic malady is an infection of pandemic extents. 1 out of 6 American work powers will be determined to have prostate threatening neoplastic illness and new examples are analyzed each 2.7 proceedingss ( Charles 2009 ) . As prostatic dangerous neoplastic illness airss such a threat to work powers around the world, more clasp and cash ought to be spent to better upon the bing techniques and building each piece great as contributed towards guidance and cognizance plans. The way that these insights are existent is the reason prostatic dangerous neoplastic illness cognizance and guidance is so imperative in light of the fact that numerous expires could hold been fo restalled if the cases had been identified at before periods of the threatening neoplastic infection. Prostate harmful neoplastic ailment ‘s explicit reason is as yet obscure, by the by researchers speculate that cistrons play a capacity, in light of the fact that the peril factor for gaining prostatic threatening neoplastic malady is well higher on the off chance that you have a family unit history of it. The two boss strategies utilized for prostate dangerous neoplastic infection testing are rectal examinations and prostate-explicit antigen ( PSA ) blood demonstrating. Rathus, Nevid, and Rathus ( 2008 ) remind work powers 50 mature ages and more seasoned that the American Cancer Society suggests that work powers get one-year rectal examinations and PSA blood preliminaries. Treatment strategies for prostate threatening neoplastic illness are constrained, yet new building has took into consideration a higher perseverance rate on account of early detecting. The primary purpose of association is that the expenses of prostatic threatening neoplastic infection mediation have gone up well in the last 20 mature ages orchestrating to USA Today journalist Lisa Szabo. In her article entitled â€Å" Patients bear brunt as harmful neoplastic infection payment hits $ 90 billion † she examines how â€Å" these lifting costs have been driven by powers, for example, new medications, mechanical medical procedures, and radiation strategies † ( 2010 ) . In her discoveries she found that from 1991 to 2002 the expense of intercession for dangerous neoplastic infection multiplied. â€Å" These augmentations are impractical † claims John Seffrin, CEO of the American Cancer Society. On account of the expanding expenses of mediation the American Cancer society can just help 1 out of 6 patients rather than in the days of old when they had the option to help 1 out of 5. At the point when one takes into history what number of harmful neoplas tic sickness patients are in the United States, so they can perceive what number of individuals are deferring mediation since they are uninsured and can non bear the cost of intercession. Unfortunately the ascent costs are following in preventable expires. In another article assessed, Krahn, Zagorski, Laporte, Alibhai, Bremner, Tomlinson, Warde, and Naglie, ( 2009 ) set out to recognize social insurance costs comparable to prostate dangerous neoplastic malady. They examined direct clinical expenses for around 42,000 work powers over the designed development of the infection. The costs they discovered were between $ 2,000 to around $ 16,000 dependant on where the single patient was in the mediation technique and how exceptional their harmful neoplastic ailment was. The following choice was that prostatic dangerous neoplastic sickness costs â€Å" are most noteworthy around two occasions, harmful neoplastic ailment diagnosing and threatening neoplastic illness expire † ( Krahn et Al ‘s. 2009 ) . The second purpose of association is that medication organization Roche ‘s â€Å" Avastin † a prostatic dangerous neoplastic malady sedate late hit features and non in a decent way. Fitting to the Wall Street Journal, Roche Holdings discharged an explanation that said that Avastin had flopped in late stage prostate threatening neoplastic ailment tests. This insight was non useful for investors who are assessed to hold lost extending gross incomes of 7.48 billion dollars. The other terrible knowledge is that individuals who have been using Avastin an immune response for mediation of harmful neoplastic illness, are other than paying for something that is non each piece strong as they have been persuade. The third purpose of association is that despite the fact that researchers comprehend what causes harmful neoplastic ailment, new stairss are being made to distinguish what explicitly causes prostatic threatening neoplastic sickness, and different sorts of dangerous neoplastic malady. In an energizing article in Science News, essayist L. Sanders audits another study that recommends likely connections between â€Å" self-restoring root cells † and prostatic threatening neoplastic infection ( 2010 ) . The study recommends that cistrons are the culprit. â€Å" Think roughly harmful neoplastic infection as an ailment of root cells, Mutants in these cells can do ordinary root cells to lose their regularized conduct and on the other hand transform into an undeveloped dangerous neoplastic malady † ( Sanders 2010 ) . The examination laborers other than found that prostatic tissue cells called â€Å" Basal root cells † are the most probable culprit in look into lab prelim inaries done on mice. You read Prostate Cancer Causes And Treatment Health And Social Care Essay in class Exposition models In all the exploration they have done, â€Å" Basal root cells are what drives the threatening neoplastic malady, independent of the kind of freak † says Owen Witte, an examination specialist at the University of California. â€Å" A particular cistron called Bmi-1 plays a significant capacity in â€Å" Basal root cells † recovery methodology, when Bmi-1 movement was diminished, the phones were not, at this point ready to self recharge, nor did they compose tumors † ( Sanders 2010 ) . The fourth purpose of contribution is that surveies show family unit history of prostate threatening neoplastic ailment as one of the taking peril factors related with prostate dangerous neoplastic ailment. As Damber and Aus ( 2008 ) found while looking into prostate harmful neoplastic malady, family unit history is a major factor when estimating 1s single risk factors. They estimate that one apparent ground for this is cistrons are passed down naturally from male parent to kid. They other than accept that the dangerous neoplastic malady doing cistrons transform, however the ground ( s ) why are as yet obscure. Blending to the content version journalists, Rathus, Nevid, and Rathus ( 2008 ) eating up high aggregates of energize being fats has been appeared to expand 1s danger of securing prostatic dangerous neoplastic malady. They other than examine how the open doors are higher in dark guys than in white guys. One thing Damber and Aus ( 2008 ) noted in their study was that the figure of cases of prostate threatening neoplastic ailment was higher in work powers in urbanized states rather than Asiatic work powers. The resulting surveies demonstrated that way of life contrasts each piece great as presentation to radiation were the justification for the various measurements between Asiatic work powers and those in increasingly urbanized states. They other than examine how PSA and other indicating techniques are as yet being concentrated too much investigate only how adequate they truly are. When work powers are associated with holding prostate threatening neoplastic malady, the most widely recognized technique for diagnosing is a biopsy which is carefully taking a little piece of the presumed tumor for demonstrating. Most patients once they are determined to have the malady, are worried about how focused the harmful neoplastic ailment is, on the grounds that it is this factor more than some other that decides to what extent they need to populate. â€Å" at the end of the day, the malady builds up the conjecture more than the pick of mediation. † ( Damber and Aus 2008 ) Treatment strategies are changed and all have perils included, however as the essayists called attention to, most intercession programs depend on components, for example, the PSA figure, ( how high or low ) the degree

Tuesday, July 14, 2020

The Link Between Early Drinking Age and Alcoholism Risk

The Link Between Early Drinking Age and Alcoholism Risk Addiction Alcohol Use Print The Link Between Early Drinking Age and Risk of Alcoholism By Buddy T facebook twitter Buddy T is an anonymous writer and founding member of the Online Al-Anon Outreach Committee with decades of experience writing about alcoholism. Learn about our editorial policy Buddy T Updated on October 02, 2019 Westend61 / Getty Images More in Addiction Alcohol Use Binge Drinking Withdrawal and Relapse Children of Alcoholics Drunk Driving Addictive Behaviors Drug Use Nicotine Use Coping and Recovery Young people who start drinking before age 15 are significantly more likely to develop alcohol use disorders as adults than those who wait until after age 18, but researchers are not sure if early-onset drinking is a marker for higher risk or a direct risk factor. Researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) examined data from a three-year study of 22,316 drinkers who are now 18 years or older. They looked at the associations between the first incidence of alcohol dependence or abuse and three age-of-first-drink groupsâ€"younger than 15, between 15 and 17, and 18 years or older. Drinking Before Age 15 Increases the Risk of Alcoholism The scientists were careful to control for other risk factors for developing drinking problems, such as family history, duration of exposure to alcohol and other childhood risk factors. The key finding of the NIAAA research was that people who started drinking before age 15 were 50% more likely to become alcohol dependent as adults. The same was true to a lesser extent for those who started drinking between ages 15 and 17. Impaired Executive Cognitive Function Past studies have often suggested that this association might result from common risk factors predisposing people to both early drinking and alcohol use disorders. Although the current study does not provide conclusive evidence that early drinking directly increases alcohol use disorder risk, it suggests that it is premature to rule out the possibility of such a direct effect. said Deborah A. Dawson, staff scientist at the NIAAA, in a news release. The NIAAA researchers believe that impaired executive cognitive function leads young people to make choices that lean toward the immediate pleasure associated with heavy drinking rather than choices to avoid the long-term risks of alcohol use disorders. But the question they have not answered is whether the impaired executive cognitive function leads to heavy early-onset drinking, or the early heavy drinking causes the impaired executive cognitive function. Alcoholism Prevention Should Target Younger Children Regardless, the NIAAA researchers conclude that prevention programs and public health policies should be targeted at children under age 15 and underage drinking, in general, to try to delay the onset of drinking alcohol as long as possible. The data support the notion of delaying the onset of drinking behavior as late as possible as an important principle for the prevention of alcohol use disorders later in life, said NIAAA researcher Howard B. Moss. More specifically, these findings provide the scientific basis for those prevention programs that focus on decreasing underage drinking, as well as supporting those public-health policies that are geared towards the prevention of underage drinking. Study Identifies Top Risk Factors for Teen Substance Abuse

Thursday, May 21, 2020

Different Forms Of Government Treat Their Citizens

The amount of power that a government should have within a country has been argued throughout history. A mutualistic relationship between a government and its people is clear in almost every society in the world, yet, the dominance one entity has over the other varies from case to case. The United States’ foundation is based upon the fact that the Government works for the people in which actual citizens take part in maintaining a fair, unified authority, but this modern democracy has many pros and cons and is still not agreeably the best form of government. People’s opinions differ on how much say any given person should have on the decisions his or her county makes and the relationship a government should have with its people is very†¦show more content†¦The most shocking part of the novel in which doublethink is implemented is when the Party suddenly announces that Oceania is at war with Eastasia and no longer Eurasia. The part that is shocking is that once t he announcement is made about the change of countries, the people unquestionably change their previous hate towards Eastasia and immediately despise their once allies Eurasia. The unconditioned trust in the government truly shows how brainwashed the population is, and because of this trust the society is able to function successfully. The true patriotism of the citizens facilitates a lack of anguish over the harsh injustices from the government; everyone in Oceania is content with a brutal lifestyle and none dare to revolt against The Party. Winston shares how society functions successfully behind such a corrupt government when he says, â€Å"In a way, the world−view of the Party imposed itself most successfully on people incapable of understanding it†Ã¢â‚¬ ¦ â€Å"By lack of understanding they remained sane. They simply swallowed everything, and what they swallowed did them no harm, because it left no residue behind† (Orwell). Since the decisions that are made i n society are done completely by the government, the citizens of Oceania have to absorb whatever the Party announces as fact. With no thoughts about how life could become better the people coexist in a habitat in which they truly believe could not be improved. All injustice and conflict is diminished once people

Wednesday, May 6, 2020

Benefits Of A College Degree - 911 Words

Luke McKnight Composition I 7 November 2014 Researchers over the years nearly all say similar things, and that is that going to college will probably give you more opportunities to make money. You don t even need a fancy degree, or study to see it. A normal person with a bachelor s degree earns about $48,000 per year, compared with $27,000 for a high school graduate. Grads also have lower unemployment, from cases of lack of education, as of November 3. The labor field has always paid a number more, for college graduates, and that rate has grown sharply over the past years. People who study these trends say that, it is mostly due to skill-needed technology growing industries. And they have been changing the distribution of skills needed by employers. For example, employers have needed a larger number of highly educated workers to match their increasingly advanced technologies, as well as clever people to be able to work in increasingly intricate and connected markets. A college degree can serve as both proof of learned skills a nd a signal of innate analytical ability Skill-biased change aids most those already at the high end of the distribution of ability and preparedness, which is why it is widely viewed as one of the leading explanations for growing income inequality. Though college enrollments have been climbing steadily the trend only seems to be increasing for the young population, wheras the older population is a bit more stable. Only some of Americans who enrollShow MoreRelatedBenefits Of A College Degree1314 Words   |  6 Pages Benefits of a College Degree Earning a college degree is such an important step in life that it has become a central part of the â€Å"American Dream†. Go to college, get a job, buy a house, raise a family. It may not always be that simple, but it all starts with your college education.Earning a college degree is all about opening up opportunities in life. It repares you, both intellectually and socially, for your career and your adult life. benefits of a college include better career opportunitiesRead MoreBenefits Of A College Degree944 Words   |  4 Pagesworld, it is hard to imagine a child who is not going to college. The expectation of a child going to school is that he or she will get a good degree in their major of interest. It will never be a non-beneficial to anyone. Everyone in top position of the nation, companies, market and, college or university always have a good degree. They could have not been there today if they did not have a degree on hand. Therefore, having a college degree makes a great impact to people’s income, personality orRead MoreBenefits of a College Degree1447 Words   |  6 PagesOf course there are obvious benefits to getting a college degree such as better salary potential, greater ability to advance in ones career, the potential for greater job stability, and of course greater job satisfaction. These are some of the main reasons why I chose to continue my education and learnin g; however, these are not the only benefits that I have experienced. In reflecting on my educational experience I find that first studying business has prepared me to understand my functions as aRead MoreBenefits Of A College Degree862 Words   |  4 PagesThe number of high school graduates to go to college has begun to steadily decline in the past few years. Recent studies have shown that now only about sixty-six percent make the jump towards getting a degree. That means almost half the number of young adults don’t apply their selves and miss out on many opportunities for a better life. College has never not been an option for me and was a constant goal to work towards. I remember as a child dreaming about growing up and going to Clemson UniversityRead MoreBenefits Of Having A College Degree956 Words   |  4 Pagesimportant it is to go to college and get a degree. Private colleges have more academic benefits than public colleges because they have technological advancemen ts that public schools do not have. The benefits of having a college degree and higher education can help a person academically, socially, and achieve more opportunities. Every student would love to have the name Harvard or Harvey Mudd on his or her diploma, but the reality is that the vast majority of students end up at colleges with far less nameRead MoreBenefits of a College Degree Essay1411 Words   |  6 Pagesstudents have to make is whether to go to college or not. There are many factors that go into one’s decision. There are pros and cons to going to college and also there are pros and cons for not going to college. But the decision that will give someone the better opportunity to have a more successful life is to go to college. The money that one will earn after getting a college degree will be more than the money a person will make without getting a college degree. As our society has continued to evolveRead MoreCollege Education Has Become A Minimum Requirement1341 Words   |  6 PagesCollege education serves as the key to a successful future for individuals who are serious about it. It provides financial security and helps a perso n build a considerable reputation. Currently, college education has become a minimum requirement in securing a job in different companies. Is college really worth it? This is a question that many students start asking as college costs rise and jobs are harder to get. Despite these minor flaws, higher education provides many advantages in the long runRead MoreBenefits Of Attending College After High School1369 Words   |  6 PagesAM 29 April 2016 Benefits of Attending College After High School There are many benefits for students choosing college as their first step in your future after high school. Earning a college degree is an important step, both personally and professionally (Hussung, 2015). Having a higher education is valuable to an individual, families, and the community as well. Students who obtain a college education often have higher lifetime earnings and experience a variety of other benefits (â€Å"How Important†)Read MoreThe Importance Of A College Degree1181 Words   |  5 PagesA college degree is a certification of completion of state and or federal scholastic requirements. A degree informs the public a person has satisfied the necessary requirements to be considered a graduate of one of the sundry levels of edifying educational attainment. â€Å"Although colleges and universities of today carry a heavy price tag, it is of great importance not to let that discourage you from obtaining a college education† (McGuire, 2011). Importance of a College Degree As a matter of factRead MoreIs College Worth The Time And Money? Essay1308 Words   |  6 PagesWilliamson CR 11 3 Dec. 2016 Is College Worth the Time and Money? Colleges are everywhere—they are advertised middle and high schools, television ads show people satisfied with their college experiences, and parents ask their children what school they want to go to. In today’s society, college is expected for many, a necessity for others. People are told the only way to further a country is to educate. With tuition being a part of college, many question if college is worth all the money when there

How Can Global Thinking Support You Free Essays

How can Global Thinking support you? Inform The Global Thinking team offers fresh perspectives on learning from our long experience in diverse local and global contexts. Inspire We provide advice and training, resources and research to bring insight, challenge perceptions and enable creative thinking for 21st Century learning. Innovate We work in partnership with clients and education specialists on practical and innovative approaches for differing teaching and learning needs. We will write a custom essay sample on How Can Global Thinking Support You? or any similar topic only for you Order Now Global Thinking provides inspiration and innovation in global learning. Our specialist team provides training and consultancy to educators who enable young people to shape their futures in a fair and sustainable world. Education The term was increasingly applied to initiatives in international education and was advanced by  Stuart Grauer  in his 1989 University of San Diego publication, Think Globally, Act Locally: A Delphi Study of Educational Leadership Through the Development of International Resources in the Local Community. In this publication it was attribed to  Harlan Cleveland. 15]  It is said that this term was used by German-American  sociologist  Eugen Rosenstock-Huessy[citation needed]  in the 1950s or earlier, prior to the formation of the  United Nations Organization. It is not only corporations that are acknowledging the importance of environmental issues, but also the education system. Government officials and school boards across the world are beginning to develop a new way of teaching. Globalization is now thought of as an important concept to understanding the world. Certain schools believe it is important to discuss global issues as young as 5 years old. It is students who are our future, therefore understanding the concept of â€Å"think globally, act locally† is fundamental to our future. [16] Definition â€Å"Think globally, act locally†Ã‚  urges people to consider the health of the entire planet and to take action in their own communities and cities. Long before governments began enforcing environmental laws, individuals were coming together to protect habitats and the organisms that live within them. These efforts are referred to as grassroots efforts. They occur on a local level and are primarily run by volunteers and helpers. â€Å"Think Globally, Act Locally† originally began at the grassroots level, however, it is now a global concept with high importance. It is not just volunteers who take the environment into consideration. It is corporations, government officials, education system, and local communities. It is now extremely important to consider global markets and communities when doing business. Global markets and large corporations have one of the largest impacts on the environment, it is their influence and actions that are vital to the survival of our planet. Large corporations have the most impact on the environment, therefore â€Å"thinking globally and acting locally† can make a major difference in the survival of our planet. Warren Heaps states â€Å"it’s really important to recognize that markets are different around the world, and company compensation programs should reflect a balance between global corporate philosophy and local practice and culture†. 1] About the Department The Faculty of Arts and Letters is an institution of learning geared towards the development and fulfillment of the total person, the Universal Man, focusing on the Arts and the Humanities, mainly, and spreading out to include the sciences, social and natural, guided by Christian faith and avowed Thomasian ideals and the highest social, national, international and even glob al standards and objectives. The envisioned goal is the Colege’s turning out not only of learned but wisened individuals who, motivated by the highest standards of excellence, excel in their chosen fields, eventually becoming role models in society, potential leaders and achievers of the country, all in the spirit not only of personal but also social and more importantly, spiritual commitment. The Faculty’s goals and objectives are: An ideal confluence of mind, heart and spirit, in the service of the total rounded man. Expertise in one’s own chosen field and an adequate spreading out of interests, skils, concerns, in other, fields, allied of otherwise. An enhanced and enriched cultural background including a sense of history and tradition while being abreast with the modern technology of a network world. Ample exposure to and immersion in research as well as creative and critical endeavors. Sympathy and concern for the socially needy and handicapped through consistent efforts and interst in community service. Constant cultivation and preservation of Philippine values at the same time cognizant of what are timeless and universal. History The liberal arts and philosophy had been taught in the University of Santo Tomas since its foundation in 1611. The Faculty of Philosophy and Letters was established in 1896 and the College of Liberal Arts in 1926. In 1964, however these two colleges were merged and given the general name of Faculty of Arts and Letters. Courses offered then were Bachelor of Arts, Bachelor of Literature, and Bachelor of Philosophy. In the course of time, new majors were offered. In the academic year 1971 to 1972, the Faculty started to offer the degree of Bachelor of Arts in Asian Studies, Behavioral Science (which evolved form the originally offered LiA-Com), Communication Arts, Economics, Journalism, Literature, Philosophy,Political Science, Sociology, and Translation(which was eventually phased out). In 1994, another major, Legal Management, was created to serve the relevant needs of students who intend to go to law after graduation. And so, presently, ten majors are offered in the Faculty of Arts and Letters to wit; Asian Studies, Behavioral Science, Communication Arts, Economics, Jouranlism, Literature, Legal Management, Political Science, Philosophy, and Sociology. Common courses offered in the Faculty of Arts and Letters are designed to develop the minds and sensibilities of the students and to inculcate in them human values and the appreciation of the country’s cultural heritage in the light of Christian faith and tradition. Furthermore, they intend to provide the students with the necessary background for them to develop into informed, responsible, and concerned rounded citizens of this country, guided by the mission-vision not only of the College but more importantly, of the University of Santo Tomas. â€Å"Mga Uri Ng Pagsulat†Ã‚  StudyMode. com. 01 2011. 01 2011 http://www. studymode. com/essays/Mga-Uri-Ng-Pagsulat-561134. html. How to cite How Can Global Thinking Support You?, Essay examples

Friday, April 24, 2020

Mozart Essays (1839 words) - Mozart Family, Wolfgang Amadeus Mozart

Mozart Wolfgang Amadeus Mozart (1756-1791) was born in Salzburg in Austria, the son of Leopold, Kapellmeister to the Prince-Archbishop of Salzburg. By the age of three he could play the piano, and he was composing by the time he was five; minuets from this period show remarkable understanding of form. Mozart's elder sister Maria Anna (best known as Nannerl) was also a gifted keyboard player, and in 1762 their father took the two prodigies on a short performing tour, of the courts at Vienna and Munich. Encouraged by their reception, they embarked the next year on a longer tour, including two weeks at Versailles, where the children enchanted Louis XV. In 1764 they arrived in London. Here Mozart wrote his first three symphonies, under the influence of Johann Christian Bach, youngest son of Johann Sebastian, who lived in the city. After their return to Salzburg there followed three trips to Italy between 1769 and 1773. In Rome Mozart heard a performance of Allegri's Misere; the score of this work was closely guarded, but Mozart managed to transcribe the music almost perfectly from memory. On Mozart's first visit to Milan, his opera Mitridate, r? di Ponto was successfully produced, followed on a subsequent visit by Lucia Silla. The latter showed signs of the rich, full orchestration that characterizes his later operas. A trip to Vienna in 1773 failed to produce the court appointment that both Mozart and his father wished for him, but did introduce Mozart to the influence of Haydn, whose Sturm und Drang string quartets (Opus 20) had recently been published. The influence is clear in Mozart's six string quartets, K168-173, and in his Symphony in G minor, K183. Another trip in search of patronage ended less happily. Accompanied by his mother, Mozart left Salzburg in 1777, travelling through Mannheim to Paris. But in July 1778 his mother died. Nor was the trip a professional success: no longer able to pass for a prodigy, Mozart's reception there was muted and hopes of a job came nothing. Back in Salzburg Mozart worked for two years as a church organist for the new archbishop. His employer was less kindly disposed to the Mozart family than his predecessor had been, but the composer nonetheless produced some of his earliest masterpieces. The famous Sinfonia concertante for violin, violo and orchestra was written in 1780, and the following year Mozart's first great stage work, the opera Idomeneo, was produced in Munich, where Mozart also wrote his Serenade for 13 wind instruments, K361. On his return from Munich, however, the hostility brewing between him and the archbishop came to a head, and Mozart resigned. On delivering his resignation he was verbally abused and eventually, physically ejected from the archbishop's residence. Without patronage, Mozart was forced to confront the perils of a freelance existence. Initially his efforts met with some success. He took up residence in Vienna and in 1782 his opera Die Entf?hrung aus dem Serail (The abdication from the Seraglio) was produced in the city and rapturously received. The same year in Vienna's St Stephen's Cathedral Mozart married Constanze Weber. Soon afterwards he initiated a series of subscription concerts at which he performed his piano concertos and improvised at the keyboard. Most of Mozart's great piano concertos were written for these concerts, including those in C, K467, A, K488 and C minor, K491. In these concertos Mozart brought to the genre a unity and diversity it had not had before, combining bold symphonic richness with passages of subtle delicacy. In 1758 Mozart dedicated to Haydn the six string quartets that now bear Haydn's name. Including in this group are the quartets known as the Hunt, which make use of hunting calls, and the Dissonance, which opens with an eerie succession of dissonant chords. Overwhelmed by their quality, Haydn confessed to Leopold Mozart, 'Before God and as an honest man I tell you that your son is the greatest composer known to me either in person or by name.' The pieces are matched in excellence in Mozart's chamber music output only by his String Quintets, outstanding among which are those in C, K515, G minor, K516 and D, K593. Also in 178 Mozart and Lorenzo da Ponte collaborated on the first of a series of operatic masterpieces. Le nozze di Figaro (The Marriage of Figaro) was begun that year and performed in 1786 to an enthusiastic audience in Vienna and even greater acclaim later in Prague. In 1787 Prague?s National Theatre saw the premiere of Don Giovanni, a moralizing version of the Don Juan legend